Iron metabolism in the Rat*
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چکیده
منابع مشابه
Iron metabolism in the cobalt-polycythemic rat.
Although the finding that cobalt can produce a polycythemia in the rat, is well known (l), the mechanism of the hematopoietic action is still obscure. Orten (2) measured the serum bilirubin concentration of normal and cobalt-polycythemic rats, from which he concluded that passive accumulation of red blood cells as a result of a diminished rate of destruction did not occur. Copp (3) found that i...
متن کاملIron metabolism in the Belgrade rat.
Iron metabolism in the Belgrade rat was examined in the intact animal and in the reticulocyte suspensions. The plasma iron turnover was increased. However, when allowance was made for the effect of the elevated plasma iron concentration, erythroid marrow capacity for iron uptake was at basal levels. Numbers of erythroid cells in marrow and spleen measured by the radioiron dilution technique wer...
متن کاملTHE RELATIONSHIP BETWEEN ALUMINIUM TOXICITY AND IRON METABOLISM IN RATS
The relationship between aluminium toxicity and iron metabolism was studied. Male rats were exposed to aluminium by daily intraperitoneal injection of 40pmolelkg body weight. After 45 days, aluminium intoxified rats had a significant loweredserum ferritin (55%), iron (42%), TIBC (25%) and hemoglobin(31%). At thesame time the serum ceruloplasmin level was elevated by 60%. This result shows t...
متن کاملFetal iron status regulates maternal iron metabolism during pregnancy in the rat.
Iron metabolism during pregnancy is biased toward maintaining the fetal supply, even at the cost of anemia in the mother. The mechanisms regulating this are not well understood. Here, we examine iron deficiency and supplementation on the hierarchy of iron supply and the gene expression of proteins that regulate iron metabolism in the rat. Dams were fed iron-deficient diets for 4 wk, mated, and ...
متن کاملAluminum taken up by transferrin-independent iron uptake affects the iron metabolism in rat cortical cells.
We previously demonstrated that cultured human fibroblasts internalize iron via transferrin-independent iron uptake (Tf-IU), redox, and receptor-mediated endocytosis uptake systems [Oshiro, S., Nakajima, H., Markello, T., Krasnewich, D., Bernardini, I., and Gahl, W.A. (1993) J. Biol. Chem. 268, 21586 21591]. Of these iron transport systems, the Tf-IU system is involved in the accumulation of tr...
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ژورنال
عنوان ژورنال: Skandinavisches Archiv Für Physiologie
سال: 1940
ISSN: 0370-839X
DOI: 10.1111/j.1748-1716.1940.tb01488.x